Vape additives that mimic nicotine are potent- and largely unregulated

The company Charlie’s Holdings, Inc. launched the new line of vaping products called Spree Bar which contain Metatine, a trademarked name for its synthetic nicotine analog, 6-methylnicotine. Because of the narrow definition of nicotine in U.S. law, the addition of one chemical structure called a methyl group allows the company to market Metatine as indistinguishable from traditional vaping products’ nicotine while also avoiding any regulatory scrutiny. Other companies are doing the same with similar nicotine analogs in vaping liquids and oral pouches.