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Wednesday . May 14

WIGAND IS QUESTIONED ABOUT THE EFFECT OF NICOTINE ON THE BODY

Q.
And the free nicotine, is that what you previously described has a pharmacological effect?
A. That is correct.
Q. In other words, it acts as a drug on the body?
MR. BEZANSON: Object to the form.
A. Yes.
MR. MOTLEY:
Q.
It acts as a drug on the body?
MR. BEZANSON: Object to the form.
A. Yes.
MR. MOTLEY:
Q.
It acts as a drug on the body.
MR. BEZANSON: Object to the form.
MR. MOTLEY: Is there an echo here? Let it carry forward.
Q. Does it act as a drug? And you can carry your objection forward.
A. Yes. It is pharmacologically active. There are a number of studies that confirm that.
Q. Studies by whom?
A. By independent scientists, by BAT scientists.
Q. That confirm that free nicotine is pharmacologically active and is a drug?
MR. BEZANSON: Object to the form.
A. Yes. It produces a physiological response, as the definition of a drug.
MR. MOTLEY:
Q.
Sir, did you learn while you were with Brown & Williamson why nicotine was important to the sale of cigarettes? You were telling us about this graph earlier, and I was wondering why the nicotine, the inclusion of nicotine was important to the ability to sell a cigarette.
A. Nicotine is associated with impact satisfaction, arousal, pharmacological effect that goes across the blood brain barrier. It possesses an order of transmitter activities. Below a certain level of .4 milligrams does not sustain satisfaction. Over 1.2 milligrams becomes too harsh and has too much of an impact, impact associated with the physiological effect associated with nicotine.

 

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